Prostaglandin Deficiency and Endorphin Excess in Schizophrenia: The Case for Treatment with Penicillin, Zinc, and Evening Primrose Oil
نویسنده
چکیده
The dominant orthodox biological concept of schizophrenia is that it is somehow related to an excess of dopamine activity in critical areas of the brain. The outstanding pieces of evidence in favor of this concept are that all the commonly used anti-schizophrenic drugs are blockers of dopamine receptors and that two groups have now reported that certain regions of the brain in schizophrenics exhibit supersensitive dopamine receptors (Owen et al., 1978). This dopamine hypothesis has been challenged by the Orthomolecular concept that schizophrenia may be related to problems in vitamin and mineral
منابع مشابه
A Trial of Evening Primrose Oil in the Treatment of Chronic Schizophrenia
Evening Primrose Oil with supplements was administered to thirteen chronic schizophrenics on a double blind cross-over basis. No significant therapeutic effect was found but there is a possibility that the EPO strategy potentiates the epileptogenic properties of the phenothiazines. D. Horrobin's proposal that there may be a deficiency of prostaglandin El (PGEl) in schizophrenia (Horrobin, 1977;...
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